FFPE MSI Characterized

Microsatellite instability (MSI) is the condition of genetic hypermutability (predisposition to mutation) that results from impaired DNA mismatch repair (MMR). MSI is associated with a plethora of cancer types, including colorectal, gastric, endometrium, ovarian, hepatobiliary tract, urinary tract, brain, and skin cancers. However, MSI is most prevalent in association with colon cancer.  BioChain has characterized many of these cancer samples using either direct PCR or indirect immunohistochemistry (IHC) with MLH-1, PMS2, MSH-2, and MSH-6 antibodies to give these control samples to the cancer research community.

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