BioChain specializes in providing a fully customizable, end-to-end, full stack process with in-house tissues, histopathology team services, digital Leica scanning, and an expert NGS data analysis team to fulfill all of your research needs. Allow spatial transcriptomics to play a pivotal role in answering your complex biological questions.
Integrate the best of spatial and molecular profiling technologies by generating whole transcriptomes and profiling data for 100s of validated protein analytes from up to 12 tissue slides per day.
Delve deeper and thoroughly assess your samples with protein, total mRNA, and morphology in the same tissue section. Visualize protein and whole transcriptome expression and much more.
The highest resolution, whole transcriptome spatial mapping tool by Curio Seeker is now available. Based on Slide-seqV2 from the Broad Institute at MIT, Curio Seeker produces continuous high-resolution gene expression maps at 10um resolution.
BioChain's spatially characterized tissues have already completed a robust spatial workflow (sample prep, imaging, library construction, sequencing, & data visualization)
The Xenium Analyzer is a robust, versatile instrument for high-throughput analysis, with onboard analysis capabilities to process image data, localize RNA and protein signals at sub-cellular resolution, and perform secondary analysis.
The field of spatial biology has seen immense growth in recent years. Spatial profiling reveals the spatial context of RNA and proteins in tissue and enables researchers to answer new complex biological questions. Spatial transcriptomics and spatial proteomics have been termed the “new frontier” in molecular biology due to the enormous promise of new discoveries.
Quantitatively understanding tissue heterogeneity is key in both the discovery and translational research. With technologies available at Biochain, you can spatially resolve the whole transcriptome or high plex protein across your tissue sample. Mapping gene and protein expression allows you to determine the function of distinct cell populations, explore how proximity affects biological response, identify new biomarkers, and profile distinct biological compartments. Answer new questions with our spatial biology services today.
Step 1: Tissue samples
Choose your tissues samples from BioChain's vast repository of ethically sourced and IRB approved tissues or send us your own preselected tissues.
Step 2: 10x Visium® or NanoString GeoMx® DSP
Work side by side with a specialized spatial biology scientist to determine which spatial path, 10x Visium® or NanoString GeoMx® DSP, best conforms to your constraints and will deliver the quality results you are looking for.
Step 3: Customize
Our team of scientists will fully customize your selected spatial process to achieve the best and the most accurate results possible.
Be assured. You and your valuable research are our utmost priority.
Be assured that your research is in the right hands. Trusted by hundreds of the world's top biotechnology companies, pharmaceutical firms, and the leading academic institutions for over 25 years, BioChain is committed to providing a responsive and a quality experience. We are here for you every step of the way.
Guiding you from beginning to end, from our in-house tissue selection to expert guided data analysis
Our two service processes are completely customizable to your every need and research expectations
Specialized in-house Histopathology & NGS teams of scientists are available to assist each step of the way
We all understand the value of quantitating protein or gene expression levels in cancer, neuroscience, and many other fields of biological discoveries. Our team of experts ensure a smooth integration of current histology methods to produce discovery-driven spatial multiomics data instantly.
Reach out to us to customize your project! We offer a fully customizable, end-to-end, full stack process able to conform to your needs.
Frozen Tissue Arrays contain a variety of human normal and tumor tissues, including FDA TMAs are available
Our repository covers a wide variety of normal, diseased and tumor blocks retrieved from animal and Human species