Biochain Introduces New Lines of HPV and Microsatellite instability (MSI) Characterized FFPE Tissue Products
To expand its characterized tissue product line, Biochain proudly introduces HPV Characterized and MSI Characterized FFPE tissue products.
FFPE HPV Characterized
HPV infection has been reported to correlate with several cancer types, especially squamous cell carcinomas originating from head and neck (H&N) as well as cervix tissues. HPVs are classified by genotype, and at least 130 types have been identified by sequencing the gene encoding the major capsid protein L1. High-risk genotypes 16 and 18 are associated with 70% of cervical, and about 80% HPV positive vulval and vaginal carcinoma. Using Diacarta’s QuantiVirus™ HPV E6/E7 RNA test, BioChain offers HPV-characterized H&N and cervix squamous cell carcinoma tissue sections from various donors as control slides for scientists in this field of study. Both positive and negative samples are available. Please follow the link below to learn more.
FFPE MSI Characterized
Microsatellite instability (MSI) is the condition of genetic hypermutability (predisposition to mutation) that results from impaired DNA mismatch repair (MMR). MSI is associated with a plethora of cancer types, including colorectal, gastric, endometrium, ovarian, hepatobiliary tract, urinary tract, brain, and skin cancers. However, MSI is most prevalent in association with colon cancer. BioChain has characterized many of these cancer samples using either direct PCR or indirect immunohistochemistry (IHC) with MLH-1, PMS2, MSH-2, and MSH-6 antibodies to give these control samples to the cancer research community. Please follow the link below to learn more.