Akt2 Regulates All Akt Isoforms and Promotes Resistance to Hypoxia through Induction of miR-21 upon Oxygen Deprivation

Christos Polytarchou, Dimitrios Iliopoulos, Maria Hatziapostolou, Filippos Kottakis, Ioanna Maroulakou, Kevin Struhl, Philip N. Tsichlis
Cancer Res. Jul 1, 2011
… …HIF-1alpha. Human ovarian cancer samples RNAs from 31 ovarian adenocarcinomas were purchased from Origene Technologies Inc. and Biochain Inc. and they were used for real-time PCR analyses. Results Akt2-expressing cells are more resistant to hypoxia than… …
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