The antimicrobial protein, CAP37, is upregulated in pyramidal neurons during Alzheimer’s disease

Amanda J. Brock, Anne Kasus-Jacobi, Megan Lerner, Sreemathi Logan, Adekunle M. Adesina, H. Anne Pereira
Springer Berlin Heidelberg Oct 1, 2015
Total RNA from primary human neurons and primary human astrocytes and total RNA from temporal, frontal, and occipital lobe tissues of patients with AD and five donor pool normal controls (Biochain, Newark, CA) were purchased from their respective commercial vendors. “PCR-ready first-strand cDNA from peripheral blood leukocytes was obtained from Biochain.” “Total protein lysates from the temporal lobe of one patient with AD (75-year-old male), from the frontal lobe of one patient with AD (83-year-old male), and from the temporal (26-year-old male) and frontal (71-year-old male) lobes of normal controls were obtained from Biochain.”

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