Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model

Sara E Gombash, Jack W Lipton, Timothy J Collier, Lalitha Madhavan, Kathy Steece-Collier, Allyson Cole-Strauss, Brian T Terpstra, Anne L Spieles-Engemann, Brian F Daley, Susan L Wohlgenant, Valerie B Thompson, Fredric P Manfredsson, Ronald J Mandel, Caryl E Sortwell
Mol. Ther. Mar 1, 2012
… Human PTN was cloned from human brain complementary DNA (BioChain Institute, Hayward, CA) and inserted into an AAV plasmid backbone downstream of a synthetic chicken ß-actin promoter/cytomegalovirus enhancer promoter hybrid. …

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