Intrapulmonary penetration of ceftolozane/tazobactam and piperacillin/tazobactam in healthy adult subjects

Gurudatt Chandorkar, Jennifer A Huntington, Mark H Gotfried, Keith A Rodvold, Obiamiwe Umeh
J. Antimicrob. Chemother. Oct 18, 2012
… The lower limit of detection for all three drugs in BAL was 1.00 ng/mL. Urea concentrations in plasma and BAL were performed at MicroConstants, Inc. (San Diego, CA, USA) using a colorimetric technique (Urea Assay Kit Z5030016, BioChain, Hayward, CA, USA). …

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