Immunotargeting of Antigen xCT Attenuates Stem-like Cell Behavior and Metastatic Progression in Breast Cancer

Stefania Lanzardo, Laura Conti, Ronald Rooke, Roberto Ruiu, Nathalie Accart, Elisabetta Bolli, Maddalena Arigoni, Marco Macagno, Giuseppina Barrera, Stefania Pizzimenti, Luigi Aurisicchio, Raffaele Adolfo Calogero,Federica Cavallo
Cancer Research Jan 1, 2016
Tumor microarrays (TMA; Biochain # T8234700-2, lot # B406087, and Biochain # T6235086-5, lot # B112136) of normal or tumor human tissues were blocked in 3% H2O2 (Sigma-Aldrich), followed by 1% BSA, and then incubated with anti-xCT or isotype-matched control antibodies (Abcam).

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