Immunization with a Vaccine Combining Herpes Simplex Virus 2 (HSV-2) Glycoprotein C (gC) and gD Subunits Improves the Protection of Dorsal Root Ganglia in Mice and Reduces the Frequency of Recurrent Vaginal Shedding of HSV-2 DNA in Guinea Pigs Compared to Immunization with gD Alone

Sita Awasthi, John M. Lubinski, Carolyn E. Shaw, Shana M. Barrett, Michael Cai, Fushan Wang, Michael Betts, Susan Kingsley, Daniel J. DiStefano, John W. Balliet, Jessica A. Flynn, Danilo R. Casimiro, Janine T. Bryan, Harvey M. Friedman
J. Virol Oct 1, 2011
… …prepared using purified HSV-2 DNA (Advanced Biotechnologies) and mouse lung genomic DNA as the source of the adipsin gene (BioChain Institute). The standard curve samples were run in triplicate wells at 50,000, 5,000, 500, 50, and 5 copies of DNA. HSV-2 DNA… …

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