EXPERIMENTAL THERAPEUTICS, MOLECULAR TARGETS, AND CHEMICAL BIOLOGY: Human Pregnane X Receptor and Resistance to Chemotherapy in Prostate Cancer

Yakun Chen, Yong Tang, Man-Tzu Wang, Su Zeng, Daotai Nie
Cancer Res. Nov 1, 2007
… …of PXR or its target genes, CYP3A4 and MDR1, was evaluated by semiquantitative RT-PCR. A normal human colon tissue sample (BioChain Institute, Inc.) and a human liver cancer cell line, HepG2, were used in parallel to compare the transcript levels of PXR in… …

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