Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs

Francesco Rua, Sheila J Sadeghi, Silvia Castrignanò, Giovanna Di Nardo, Gianfranco Gilardi
J. Inorg. Biochem. Dec 15, 2012
… Sigma-Aldrich (Italy). 2.2. Cloning of recombinant P450 2C20 and P450 2C20/BMR. The gene coding for the M. fascicularis P450 2C20 was amplified from the liver cDNA pool of M. fascicularis (BioChain, UK). The primers used …

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