Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice

Ri-Yao Yang, Lan Yu, James L. Graham, Daniel K. Hsu, K. C. Kent Lloyd, Peter J. Havel, Fu-Tong Liu
PNAS Oct 1, 2011
… …Lgals12-/- mice. IgG was purified from immunized mouse sera by affinity chromatography on an rProtein A-Se- pharose column (Biochain). The specificity of these antibodies was clearly demonstrated by their recognition of a single protein band with a molecular… …

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