FFPE Tissue Array

As it can be expensive and time-consuming to perform histology tests on multiple cancerous and normal ffpe tissue array slides, BioChain produces a wide variety of formalin fixed, paraffin embedded tissue arrays and tissue microarrays (TMAs).  These are useful tools that can be used for the validation of biological targets, and evaluation of their potential clinical relevance in the development of diagnostics or therapeutics.

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FFPE Tissue Array

Each array or TMA contains dozens of tissue cores fixed to the same positively charged slide.  These cores can come from a selection of normal tissues, or from a selection of pathologically relevant cancer tumors, of different stages, from multiple donors.  In addition to our human tissue products, some arrays and microarrays include cores from FFPE tissues harvested from the same organs from multiple species, or from multiple organs from the same non-human species.  In some cases we may have DNA, RNA, or protein isolates that correspond to a particular array.  To find out what we can offer, please call us.

In addition to the materials listed in our catalog, we frequently create custom arrays that are tailored to the needs of our customers.  We can procure tissue, produce cores (of a selection of sizes), produce paraffin blocks containing these cores, cut sections from these blocks, and fix them to slides.  We are also happy to perform just some of these steps – such as creating a TMA block from tissues provided by a customer.  Other custom services include isolation of DNA, RNA, or protein from the same tissues or cores as those used to produce a custom array or TMA.

BioChain’s FFPE tissue arrays allow for histological analyses of multiple cancerous tissues on a single slide, or in some cases two slides – saving time and preserving expensive reagents. They can also be used to study new protein, DNA and RNA markers, and disease related genes. Therefore, our FFPE tissue arrays provide high throughput platforms for the rapid investigation of biomarkers associated with oncology, diagnosis, and disease therapeutics.  We are also happy to take on custom projects.

Features FFPE Tissue Array

  • Manufactured using high quality tissue cores
  • Suitable for in situ hybridization and immunohistochemistry
  • Ready-to-use
  • Both radioactive and non-radioactive detection
  • Corresponding RNA, DNA, cDNA, or protein available
  • Broad coverage of tissue types
  • Fresh cut sections available

Applications of FFPE Tissue Array

  • Antibody characterization
  • Biomarker screening
  • Drug discovery and target validation
  • Companion diagnostics development
  • Gene and protein expression analysis
  • Immunohistochemistry (IHC) and In situ hybridization (ISH)

Quality Control of FFPE Tissue Array

  • At least one of the tissue slides from each lot was stained with H & E to ensure the quality


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