BioChain’s tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation.
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Characterized Tissues
BioChain offers a large inventory of characterized tissue for your oncology research.
- Our CancerSeq line of product includes tissues that have been sequenced for hotspot mutations from a panel of cancer-related genes. Other important information such as copy number variations and the presence of RNA fusions have also been determined.
- We also provide a selection of tumor samples that have been characterized for HPV positivity using branched DNA technology.
- Finally, several adenocarcinoma tissues may be purchased that have known microsatellite instability (MSI) status. Reach out to us for custom characterized samples or custom characterizations NSG assays.
Features
- Deep sequencing by NGS with high coverage
- FFPE curls or slides available (inquire for blocks)
- Documentation of the tissue donor’s clinical histories is available
- Information regarding tumor type is available
- Complete NGS sequencing data available
Applications
- Validation of cancer marker mutation related drug candidates
- Controls or verification for genotyping
- Companion diagnostic assay development
- Suitable for both IHC and in-situ hybridization assays
- Cellular localization of tissue specific mRNA and protein expression
- Isolation of DNA and RNA with specific mutation profiles
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