Membrane Protein

Membrane proteins are an integral part of molecular biology research. These proteins interact with biological membranes to perform a variety of functions critical to the survival of the organism, including signal transduction, transport, cell adhesion, and enzymatic activity. Moreover, membrane proteins are encoded by approximately 20 – 30% of genes within a genome and are also the targets of over 50% of all modern medicinal drugs.

Learn more

Membrane Protein

At BioChain, we use proprietary isolation techniques to extract membrane proteins from a large variety of documented quality tissues. Our method begins from whole tissue homogenates and protects the protein as it is being isolated and stored, so you can be assured of the highest quality possible for each sample type. For example, running our membrane protein products on SDS-PAGE gels results in sharp bands that span a broad range of sizes with the absence of smearing. These protein lysates have also been tested for quality on a Western blot by probing against Na+/K+ ATPase.

Our membrane proteins are useful tools in the proteomics field for accelerating gene expression analysis by identifying tumor- or disease-specific membrane proteins (e.g. cell signaling receptors) and genes. Two powerful applications such as 2D-PAGE and LC-MS/MS may be used on our membrane protein products to facilitate this novel biomarker discovery. Such membrane protein research may also facilitate drug discovery experiments. Our membrane protein products are also ready for use in immunoprecipitation experiments to study protein-protein interactions, and they may be utilized for enzymatic activity analysis experiments.

We have a comprehensive collection of normal, diseased, and tumor tissues from a wide variety of species to choose from. We also offer custom procurement and collection services, so that you can be sure to obtain exactly the protein extracts that you need. If you require total protein tissue lysates, BioChain also offers a large catalog of these products to choose from here.

Therefore, we can save you valuable research time and money by eliminating the hassle of locating and extracting membrane protein fractions from a variety of sample types. Our procurement services can also help you find rare materials – enabling you to perform experiments that you thought were impossible.

Applications of Membrane Proteins

  • Tumor- and disease-specific protein biomarker discovery
  • Electrophoresis and Western blot
  • Immunoprecipitation and protein-protein interaction
  • Enzymatic activity analysis

Advantages and Features of Our Membrane Proteins

  • Extensive quality control procedures to ensure high quality membrane proteins
  • Ready-to-use in many proteomics applications
  • Decontamination of polysaccharide, proteoglycan, RNase, and genomic DNA
  • Large selection of membrane protein fractions from various samples sources and species to choose from

Quality Data

Let BioChain provide you with the highest quality membrane protein products. Our strict quality control procedures consistently result in products of intact membrane proteins with verification of protein expression on a Western blot (Figure 1).

membrane proteins

Figure 1. Membrane Protein lysates from 3 lots of human brain tissue were run on SDS-PAGE (left). Consistent expression of Na+/K+ ATPase was visualized using a Western blot (right).


Our team of scientists are here to help!