Mutation Quantification Control Plasma
BioChain provides DNA-free DNA plasma with spiked in Synthetic ctDNAs at fixed allele frequency (AF%) mixed with normal gDNA fragments. The product includes more than 50 mutant genes partially listed in the table below. This control plasma is more “patient-like “ in process validation and quality control.
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Mutation Quantification Control Plasma
EGFR (T790M) | KRAS (G12S) | TP53 (R175H) | EGFR (delE746-A750) |
EGFR (C797S) | KRAS (G12A) | APC (R1450X) | EGFR (delL747-T751insS) |
EGFR (T790M & C797S cis) | KRAS (G12R) | Beta2-M (M1I) | EGFR (delL747-P753insS) |
EGFR (G719S) | KRAS (G13D) | DDR2 (R709X) | EML4-ALK v1 |
EGFR (G719C) | BRAF (V600E) | ERBB4 (R711C) | EML4-ALK v2 |
EGFR (G719A) | BRCA1 (P871L) | MDM2 (R189H) | ETV6-NTRK3 |
EGFR (S720F) | BRCA2 (N372H) | MDM4 (Q118L) | CCDC6-RET |
EGFR (L858R) | ERBB2 (S310F) | POLE (P286R) | NCOA4-RET |
EGFR (L861Q) | JAK2 (V617F) | PTEN (R130G) | CD74-ROS1 |
EGFR (L861R) | MAP2K1 (P124S) | SKT11 (F354L) | SLC34A2-ROS1 |
KRAS (G12D) | MET (Y1253D) | EGFR (D770-N771insNPG) | CD74-ROS1 |
KRAS (G12V) | PIK3CA (H1047R) | EGFR (D770-N771insSVQ) | CTNNB1 (S45P) |
KRAS (G12C) | TERT (A305A) | EGFR (D770-N771insG) | Beta2-M (M1I ) |