New Products

Control Genomic DNAs (Jan. 2009)
BioChain's Control Genomic DNAs are isolated from human and different animal species, genomic DNAs from male and female of each species are available.

DNA Methylation Detection Kit (Nov. 2008)
BioChain's DNA methylation detection kit offers a fast, efficient and convenient alternative to traditional bisulfite conversions. Our kit provides users with a true endogenous human positive control which eliminates any ambiguity in validating results. The positive control has been tested in over 15 different human tissues. We have optimized our protocol to minimize DNA degradation, reagent preparation, and conversion time. Our protocol guarantees > 99 % conversion of cytosine to uracil and > 99 % CpG protection, as calculated by sequencing, and is sensitive over a range of 2 µg - 500 pg of DNA. In less than 3 hours, users can obtain high quality bisulfite modified DNA ready for analysis by PCR, sequencing, or microarrays.

FFPE Tissue DNA Extraction Kit (Nov. 2008)
BioChain's FFPE Tissue DNA Extraction Kit allows for facile and efficient deoxyribonucleic acid extraction from FFPE tissues. All necessary reagents for DNA extractions in FFPE tissue specimens are provided, including FFPE tissue lysis buffer, proteinase K, and an actin control primer for control qPCR reactions. The kit contains sufficient reagents for 100 FFPE tissue DNA extraction reactions.

FFPE Tissue RNA Extraction Kit (Nov. 2008)
BioChain's FFPE Tissue RNA Extraction Kit allows for facile and efficient ribonucleic acid extraction from FFPE tissues. All necessary reagents for RNA extractions in FFPE tissue specimens are provided, including FFPE tissue lysis buffer, proteinase K, and an actin control primer for control RT-qPCR reactions. The kit contains sufficient reagents for 100 FFPE tissue RNA extraction reactions.

Blood DNA Isolation Kit (Nov. 2008)
BioChain's Blood DNA Isolation Kit offers a fast, efficient, and convenient alternative to traditional phenol or protease treatment. Our protocol guarantees isolate DNA from 50 µl to 200 µl whole blood sample. In less than 15 minutes, users can obtain pure DNA (>20kb) ready for analysis by PCR, sequencing, or microarrays.

Serum DNA Isolation Kit (Nov. 2008)
BioChain's Serum DNA Isolation kit offers a fast, efficient, and convenient alternative to traditional phenol or protease treatment. Our protocol guarantees isolate DNA from 200 µl serum or plasma samples. In less than 15 minutes, users can obtain pure DNA ready for analysis by PCR, sequencing, or microarrays.

Calcium Channel Cell Lines (Oct. 2008)
Voltage-gated calcium channels control both electrical signal transduction and intracellular calcium level. They can be generally classified into three families, designated as CaV1~3 families. T-type Ca2+ channels, or low-voltage-activated calcium channels, belong to the CaV3 family ion channels. They are activated upon minute voltage changes near the resting membrane potential. Their activation has been shown to mediate cardiac action potential, neuronal rebound burst firing and synchronization of thalamic activity; their dysfunction has been associated with various neurological and cardiovascular disorders. Their interaction with potential antagonists and inhibitors has been associated with pharmacological treatments for pain and epilepsy.

Rodent Custom Services (Oct. 2008)
BioChain has completed the establishment of a rodent facility in the San Francisco Bay area. Our facility is currently hosting major strains of inbred and outbred mice, rats, and hamsters. Our facility is fully AAALAC accredited. With our state-of-the-art facility and experienced scientists and technicians, we are well-positioned as a premium service provider in contract animal research. BioChain Institute is dedicated to providing our clients a wide range of preclinical contract animal research services designed to support various biological and pharmaceutical studies. These services range from pharmacokinetics, toxicology studies to the complete outsourcing of entire animal studies.

Mouse Feeder Cells (Sep. 2008)
Biochain provides mouse embryonic fibroblast (MEF) cells as feeder layers for stem cell culture to the research community. We have a wide range of selection of MEF cells including neomycin resistant, DR4 (resistant to neomycin, hygromycin, puromycin and 6-thioguanine) and CF-1 MEF cells. We have both untreated or gamma irradiated MEF cells. Every single batch of MEF cells is tested for its ability to support undifferentiated mESC growth and is mycoplasma negative. Early passages (P2) are provided for further expansion if more cells are needed.

Xenograft Service (Sep. 2008)
Living Tumor xenograft models are developed using human tumor tissues grafted in subrenal capsules of SCID mice. The human tumor tissues are developed into transplantable tumor tissue lines. These tumor tissue lines offer a sustainable tumor source for xenograft models. The model is in many aspects superior to conventional tumor model systems which are based on cultured cancer cell lines. There are over 100 established tumor lines available from Biochain.

Primate Animal Model Services (Sep. 2008)
 According to FDA regulations, all drug candidates for Neurological diseases, such as Alzheimer's disease and Parkinson's disease, must pass nonhuman primate animal tests before processing into clinical trials.  In addition, all cell-based therapies and gene-therapies are also required to go through nonhuman primate animal tests before advancing to a phase I clinical trial.  Nonhuman primate animal models need to be established for the research of the following important human diseases, such as AIDS, SARS, autoimmune system diseases, old age diseases, and other gene defective diseases. Biochain has teamed up with contract research organizations (CROs), which are fully accredited by AAALAC international, and exclusively focus on primate resources.  We have a very strong team of scientists, researchers, veterinarians, and technicians, who are actively engaged in developing nonhuman primate models for studies of drug safety, drug pharmacokinetics, drug efficacy, and cell and gene therapies, particularly for neurological disorders and aging-related diseases.